Breaking Bad is a drama about Walter White, a chemistry professor who is diagnosed with lung cancer. He enlists the help of his former student Jesse Pinkman to manufacture and sell methamphetamine. AMC 2008-???
Buffy the Vampire Slayer is a drama about a young girl who inherits the powers to fight the demons that threaten the Earth. She lives in Sunnydale, California which happens to be the Hellmouth and must learn to master her powers while also trying to have some semblance of a normal life. The WB 1997 - 2001. UPN 2002-03.
Shameless is a comic drama about the impoverished Gallagher family living in suburban Chicago. Alcoholic-absentee father Frank is nominally patriarch of the family but the real work is done by daughter Fiona. Then Lip, Ian, Debbie, Carl and Liam make up the rest of the family. Showtime 2011 - ???
Spartacus is a drama about a Thracian soldier imprisoned by the Roman Republic around the turn of the 1st century BC. He is sold into slavery and trained to be a gladiator in the city of Capua. STARZ 2010-???